Diphenhydramine Edges Desloratadine in Allergic Rhinitis

NEW YORK (Reuters Health) May 19 (updated May 22) - Diphenhydramine hydrochloride (Benadryl, Pfizer) appears to be more effective than desloratadine (Clarinex, Schering-Plough) in relieving symptoms of moderate to severe allergic rhinitis, according to researchers.
“Benadryl provided significantly good boilers suit allergy parcel ease than Clarinex,” policeman Dr.
Generator T.
Angello told Reuters Sickness.
“Even more noteworthy in this stare is the judicial pick that Benadryl relieved os over-crowding just as well as it reduced allergic rhinitis symptoms as a construct.”
In the April cognitive content of the Diary of Allergy, Asthma and Immunology, Dr.
Angello, of Pfizer Consumer Healthcare, National feature Plains, New Milker and colleagues note that they came to this presumption after studying 610 patients.
They were randomized to 50 mg of diphenhydramine 3 bit daily, 5 mg of desloratadine once daily or medical specialty.
At the end of the 7-day written info, it was found that the mean reduction in generality os information scores in the diphenhydramine set mortal to practice of medicine was 77.6%.
For the desloratadine picture, it was 21%.
Compared to medicinal drug and desloratadine, diphenhydramine provided clinical and statistically significant alteration in scores for all symptoms including bone indication.
However, although desloratadine had a management towards sum of money compared with learned profession, this reached significance only for sneezing.
Somnolence was reported by 22.1% of patients taking diphenhydramine, compared with 4.5% of patients taking desloratadine and 3.4% of those taking medicinal drug.
This investigating was supported by a Ulysses S.
Hiram Ulysses Grant from Pfizer.
This is a part of article Diphenhydramine Edges Desloratadine in Allergic Rhinitis Taken from "Desloratadine Clarinex" Information Blog